COST854

Protozoal reproduction losses in farm ruminants

Completed

Type of Structure:	coordinated project
Regional Scope:	continental in the area: Europe
Parent Organisations:	COST
Child Organisations:
Duration :	2002 to 2006 COMPLETED
Contact Address:	no office contact defined

General information and objectives

The main objective of the Action is to develop strategies to control reproductive diseases caused by   protozoa in farm ruminants.
The following main topics will be covered:

1. Biology, biochemistry and genetic background of virulence
Study biological and biochemical key factors determining infection and disease

Characterise parasite surface molecules that interact with the host cell

Characterise the interplay of metabolic products of the parasite with the host cell

Understand parasite differentiation from tachyzoite to bradyzoite, and vice versa (in the case of N. caninum, T. gondii and Sarcocystis spp.).
Determine the genetic background of virulence

2. Pathogenesis and host immune responses

Define and compare the development of pathology in the different animal hosts

Determine the relative role of the immune responses of the dam and the foetus and their effect on infection, transmission and disease (in the case of N. caninum, T. gondii and Sarcocystis spp.)

Determine the relative role of the immune responses of the dam in pathology or to control or prevent mucosal T. foetus infection

Identify protective and diagnostic antigens

3. Diagnosis

Identify and improve tools to diagnose infection and/or disease

Standardise diagnostic techniques

4. Epidemiology, economics and control

Define the prevalence and/or incidence of infection or disease

Identify risk factors

Calculate the economic losses on farm ruminant production

Develop cost-effective preventive and therapeutic control measures

These topics (1-4) will also become the titles of the working groups.


Last update: 4/27/22
Source of data: ProClim- Research InfoSystem (1993-2024)

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