COST854
Protozoal reproduction losses in farm ruminants
Completed
Type of Structure: |
coordinated project |
Regional Scope: |
continental
in the area: Europe
|
Parent Organisations: |
COST |
Child Organisations: |
|
Duration : |
2002 to 2006 COMPLETED |
Contact Address: |
no office contact defined |
General information and objectives
The main objective of the Action is to develop strategies to control reproductive diseases caused by protozoa in farm ruminants.
The following main topics will be covered:
1. Biology, biochemistry and genetic background of virulence
Study biological and biochemical key factors determining infection and disease
Characterise parasite surface molecules that interact with the host cell Characterise the interplay of metabolic products of the parasite with the host cell Understand parasite differentiation from tachyzoite to bradyzoite, and vice versa (in the case of N. caninum, T. gondii and Sarcocystis spp.).
Determine the genetic background of virulence
2. Pathogenesis and host immune responses Define and compare the development of pathology in the different animal hosts Determine the relative role of the immune responses of the dam and the foetus and their effect on infection, transmission and disease (in the case of N. caninum, T. gondii and Sarcocystis spp.) Determine the relative role of the immune responses of the dam in pathology or to control or prevent mucosal T. foetus infection Identify protective and diagnostic antigens
3. Diagnosis Identify and improve tools to diagnose infection and/or disease Standardise diagnostic techniques
4. Epidemiology, economics and control Define the prevalence and/or incidence of infection or disease Identify risk factors Calculate the economic losses on farm ruminant production Develop cost-effective preventive and therapeutic control measures
These topics (1-4) will also become the titles of the working groups.
Last update: 4/27/22
Source of data: ProClim- Research InfoSystem (1993-2024)
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